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For many months, Barack Obama relied on a speech that last year vaulted him from the ranks of the Democratic presidential candidates to the lead position. But in recent days, he has found it necessary to revise and revamp.

President-elect Barack Obama has named Mary Schapiro to head the Securities and Exchange Commission. In a news conference in Chicago, Obama said government regulators "had dropped the ball," leading to the financial meltdown.

The chief U.S. diplomat in Africa ratcheted up the language against Zimbabwe's longtime president Robert Mugabe on Sunday. Assistant Secretary of State Jendayi Frazer says the United States won't lift sanctions against that country until Mugabe is gone. NPR's Charlayne Hunter-Gault talks to host Andrea Seabrook about the developments.

In Fort Hood, Texas, investigators are collecting information about Thursday's deadly attack at a soldier processing center. Thirteen people were killed, 12 of them soldiers, and 30 were wounded when a gunman, identified as Army psychiatrist Maj. Nidal Malik Hasan, opened fire in the facility.

Allegations of fraud have marred Afghanistan's presidential election. Ronald Neumann, former U.S. ambassador to Afghanistan, says despite the allegations it is worth it for the White house to maintain support for Afghanistan.

The arthritis drug Humira has been a blockbuster seller for more than two decades. Now some copycats could end Humira's reign.

President Obama challenged leaders gathered at the U.N. General Assembly on Wednesday to join the U.S. in solving the world's problems rather than waiting for America to do it on its own. Obama used his first address to the U.N. General Assembly to calls for a "new era of engagement."

U.N. and Afghan officials confirmed reports of fraud in the Aug. 20 presidential elections and ordered a partial recount. The latest returns from the Afghan Election Commission show incumbent President Hamid Karzai now has enough votes to avoid a run-off with his nearest challenger.

Representatives from the U.S. and five other world powers outlined their concerns about Iran's nuclear program at a meeting in Switzerland with an Iranian delegation. U.S. officials held the highest-level direct talks with the Iranians in years.

President Obama said Tuesday Democrats and Republicans should be able to come together and pass a jobs bill. The comments came at a meeting with congressional leaders from both parties.